Which of the following is a best practice when dealing with a spill of hazardous materials?

The best practice when dealing with a spill of hazardous materials is to follow emergency response protocols and secure the area. This approach is essential because it prioritizes safety for all individuals in proximity to the spill. Securing the area helps to prevent unauthorized access and minimizes the risk of exposure to harmful substances. By implementing emergency response protocols, organizations ensure that trained personnel are alerted and appropriate measures are taken to mitigate the danger, such as containment, cleanup, and informing relevant authorities.

This method aligns with established safety procedures designed to manage hazardous spills effectively, emphasizing preparedness and the importance of acting decisively without exacerbating the situation. Other options, such as ignoring the spill or attempting to clean it up with water, can lead to increased risk and potential harm, while moving materials without securing the area may spread the hazard further.